Heart disease is the No. 1 killer in the world. Heart disease and strokes kill more than 786,000 Americans annually, according to the American Heart Association. That figure is larger than the population of several states, including North Dakota and Wyoming. Innovations in medical devices are giving heart disease patients more options, and strategic buyers are snatching up device makers.

There are “huge unmet needs” among patients of heart disease, Edwards Lifesciences CEO Michael Mussallem told investors. “As well as they’re treated today, there’s so much more opportunity.”

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