By most accounts 2021 was a chartbuster year in M&A, and buyers, sellers and investors in most sectors had a busy — if not exhaustive — year. The sector saw 4,200 deals and nearly $190 billion in total capital invested in 2021, according to PitchBook. Low interest rates, coupled with anticipation of rising U.S. capital gains tax rates, sped up deal activity, and consumer spending remained robust, says CohnReznick in its Q1 2022 Health & Wellness Investment Report. But 2022 started out differently with 669 deals and almost $23 billion in capital invested. What will happen next?

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