McKesson Corp. (NYSE: MCK) will acquire PSS World Medical Inc. (Nasdaq: PSSI) for $2.1 billion, including debt assumption.

The San Francisco-based buyer, a healthcare services and information technology company, will pay $29 per share for PSS World’s stock. The company provides surgical supplies and distributes medication.

PSS World, headquartered in Jacksonville, Fla., markets and distributes medical products to doctors in the U.S.

McKesson’s last acquisition was U.S. Oncology, which is a network that unites cancer-treatment centers, for $2.16 billion in 2010.

The deal is McKesson’s largest since it spent $2.16 billion in November 2011 for Woodlands, Texas-based US Oncology.